Connective tissue metabolism in chikungunya patients

Metabolism of the mucopolysaccharides of connective tissue.

Connective tissue metabolism and gingival overgrowth.

Gingival overgrowth occurs mainly as a result of certain anti-seizure, immunosuppressive, or antihypertensive drug therapies. Excess gingival tissues impede oral function and are disfiguring. Effective oral hygiene is compromised in the presence of gingival overgrowth, and it is now recognized that this may have negative implications for the systemic health of affected patients. Recent studies ...

Macromolecular interactions and connective-tissue metabolism.

of aortic cells, the pinocytosis proceeded with high efficiency. The uptake remained linear with time for at most 24h and then reached a plateau, probably owing to the competition for uptake by newly secreted unlabelled proteoglycans. A considerable amount of added proteoglycans, however, became associated with the cell surface (pericellular pool of glycosaminoglycans) and are not removed by re...

Studies on the Metabolism of Connective Tissue.

A granuloma pouch was formed on the back of rats by the original method of SELYE. Seven days when granuloma tissue reached its maximum, 35S labeled ChS, 59Fe labeled ChS-Fe, labeled ferric ammoninum citrate and colloidal 198Au were injected into the pouch and their absorption and organ distribution examined and compared with the results in the case where 59Fe labeled ferric ammoninum citrate an...

Metabolism of connective tissue in limb atrophy in the rabbit.

In previous experiments in adult rats (Slack, 1954, 1955), massive tissue atrophy was induced by denervation and femoral head dislocation of one hind limb. A study of the metabolism of total collagen, total sulphated polysaccharide, and mixed muscle protein indicated that disuse atrophy does not imply cessation of all protein or polysaccharide synthesis. After the onset of atrophy some synthesi...